Jung Byun, Ph.D.
Dr. Jung S. Byun is the lead investigator in seminal work that characterized the role of histone acetyltransferase, p300, and the Eleven-nineteen Lysine-rich Leukemia protein (ELL) in the control of key regulatory phases in the RNA polymerase II transcription cycle. Her work was one of the first to demonstrate the action of p300 in a form of gene expression priming, referred to as dynamic bookmarking, where p300 and RNA polymerase II form complexes that facilitate transcriptional gene expression memory at selected classes of genes. Dr. Byun is currently the cohort project manager and genome program administrator responsible for coordinating the analysis of a number of collaborative studies with NIMHD. This study incorporates a broad array of molecular analysis including exome-sequencing and/or RNA-sequencing in multiple health disparity cohorts.
Dr. Byun received her Ph.D. in Chemistry and Biochemistry from the University of Maryland, College Park. Prior to coming to NIMHD, she pursued postdoctoral studies and advanced research as a staff scientist at National Cancer Institute to investigate the roles of epigenetic regulation in the control of gene expression.
- Byun JS, Park S, Caban A, Jones A, Gardner K. Linking Race, Cancer Outcomes and Tissue Repair. American Journal of Pathology. Nov. 2017
- Byun JS, Fufa T, Wakano C, Fernandez A, Haggerty CM, Sung, MH, Gardner K. ELL facilitates RNA polymerase II pause site entry and release. Nature Commun. Jan 2012.
- Byun JS, Wong MM, Cui W, Idelman G, Li Q, De Siervi A, Bilke S, Haggerty CM, Player A, Wang YH, Thirman MJ, Kaberlein JJ, Petrovas C, Koup RA, Longo D, Ozato K, Gardner K. Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes. PNAS. 2009.